- The Old Town of Rhodes The monuments built by the Knights of St. John some 700 years ago draw as many visitors to Rhodes as the beaches do; Rhodes's Old Town is a remarkably well-preserved and photogenic testimony to its Crusader past.
- The Asklepieion Kos's site of ancient healing, the Asklepieion, was the renowned medical school founded by Hippocrates, father of Western medicine.
- Natural Wonders The terrain yields butterflies (Rhodes), hot sea springs (Kos), countless coves (Patmos), and mountain paths (Symi).
- St. John's Patmos Called the "Jerusalem of the Aegean," Patmos is as peaceful as it was when the Apostle John glimpsed the Apocalypse in his cave here—the spiritual mystique of this little island is still strong.
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