Planning our honeymoon August/September 2019 (I know last minute!)
Both of us are Italian and speak fluent which is why I thought having a car for some of the trip would be good - looking for other's who have maybe done the same?
Trip total 22 days without travel days to and from Canada.
Planning to fly into Sicily to see family for 6 days - here we thought a car would be necessary to get around from town to town.

We want to then fly from Catania to Naples - here is where I am not sure if we should have a car or not.
We want to stay at least one night in Naples (and of course have a Neapolitan Pizza!)
From Naples, we want to make our way down the coast towards the Amalfi.
We splurged on 1 hotel in Praino for 1 night and was thinking to stay somewhere close to it for the 2 days prior - or maybe 2 nights total on the coast is sufficient for a couple on a budget?
Any recommendations? Debating about having our car for this trip although I have heard that public transportation would be best.
How would you get from Naples down to a hotel on the Amalfi? Is private car service the best?
From Praino we want to get to Rome - I have heard that train is best? Recommendation is appreciated.

In Rome we plan to stay for 3 or 4 nights - of course all by foot and no car.

From Rome, we want to visit the Hot Springs in Saturnia - would you recommend renting a car on the outsides of Rome and driving there?
We could maybe stay at a hotel for 1 night here.
Next day we want to keep going, up towards Florence - but not in Florence.
We are more interested in exploring the country side then then sight seeing in Florence.
Any recommendations of where to stay?
We also want to make sure we can drop our car off and then hop on a train to go to Venice.

We plan to finish our trip in Venice - 3 nights.

I would appreciate you comments!!

I think you have two many one-night stays in your itinerary. By the time you get to the hotel and get settled in, the day is pretty much shot, and then the next day you have to hit the road again.

For example, you're thinking of spending one night in Naples, one night in Praiano, and two nights somewhere else in the vicinity. One night in Naples is probably all right, if you just want to have a pizza. However, I would try to spend the next three nights in the same place. If Praiano is too much of a splurge for three nights, why not cancel that hotel and get a more affordable one for three nights? I can't really tell you how many days is enough for the Amalfi Coast without knowing what you want to do there.

To get to Rome from the Amalfi Coast, you can get a private driver to take you to Naples; or else take a bus to Sorrento, and a little comuter train to Naples, From Naples you can get a fast train to Rome. It's a longish trip by public transportation, with two changes of bus/train.

Three or four nights in Rome might be plenty, as long as you don't try to see all of the top sights in the city. All of these top sights are extremely crowded, and usually very hot at that time of the year. Try to visit the one place you've always wanted to see, and then spend the rest of the time enjoying the hidden gems of the city, or just relaxing.

We visited the hot springs of Saturnia when we were staying just outside of Pitigliano, a very charming town that is an incredible sight when seen from the plain below. You could stay in this area for several nights, and explore the countryside from a base there without changing hotels. A car rental would be best. You could take a train from Rome to Chiusi and rent a car there. Then you could return it there, and take a train from Chiusi-Chianciano Terme to Florence. If you're not terribly interested in Florence, two nights there would give you plenty of time to get a glimpse of the city. If you can manage to arrive early, one night might be enough.

When traveling by train and bus, it's important not to be burdened by excessive luggage.

I'd like to mention the place we stayed just outside of Pitigliano, the Agriturismo Eco-Bio Villa Vacasio. We had a charming room with a private entry and a small terrace. There is a large "great room" where they serve breakfast, and also dinner if you like. The food was fantastic, and most of it came from their own farm. The owner will also give cooking lessons if requested. They have a pool, although we didn't use it in late September. It was just a very special place.

Yes to the car in Sicily.
Choose a place to stay on the AC or Bay of Naples that is easy to go to by train. Don-t waste time changing hotels there.The Circumvesuvianna is the commuter train, is cheap, easy and direct. If you plan to be out doing things, then the hotel might not be that important. We often stay in Sorrento, on the bay, because it is easy to take the ferry down the AC to Positano and Amalfi and over to Capri. It is easy to go by train to Pompeii and cheap to take the train to and from Naples. No need for a private driver. There is a lot to see and do on the AC. Seeing the Coast by boat is wonderful. Allow a day. I would not want to miss Pompeii while right there. Herculaneum is also very worth seeing. You will actually pass Pompeii and Herculaneum between Naples and anyplace on the Bay or AC.
A car again in Tuscany will be good.

This is great information - taking you advice and will cancel the 1 night booked in Praino.
I think that is making it more difficult than it needs to be.
Would you recommend Sorrento as the home base? We will likely want to do a day trip over to the Amalfi or Positano and I see you mention the Ferry is the best way of transportation.

Just another thought, with money saving in mind:

From Naples, take the train to Salerno. There are direct trains that take less than an hour. Then from Salerno, bus to the town of Amalfi. You can also take a boat or bus from Amalfi to Positano.
If you can find less expensive accomodations (I would go for a B&B or a rental if available), you will save a lot over the private car and driver option, and see a lot more. I think this option would be cheaper and provide you with more time to see the Amalfi Coast than staying in Sorrento or getting a driver to Praiano.
Do stay two nights.

Agree that Salerno could be a good stop. You just have to figure out what you want to do and see while in the area, then the best way to do it. I prefer ferries because in hot weather, I do not want to be in heavy traffic on curvy roads in a bus. The views are spectacular from both the water and cliff top drive on the AC. I give the edge to views from above, but it is cooler and more pleasant on the water. If you can do a bit of both, great. Regardless, you do not need a driver from Naples, and you might need more time on the AC. Sorrento is super touristy and busy and many see it as having less charm than places on the AC. I have stayed there several times for the convenience of easily doing a lot of sightseeing, but also stay away from the city center in more charming places up in the hills. If I want to hang out and simply relax in a beautiful place, then I choose further down on the AC. If you are only stopping in Naples for pizza, do not take the time for a night. That said, I love Naples as a city, it is so vibrant and has some great museums.

A train ride from Catania to Salerno might be more scenic than a flight.
May be Catania dp 8.41 - Taormina dp 9.19 - Messina dp 10.15 - Salerno ar 15.34. Connecting bus Salerno dp 16.30 - Praiano ar 18.25.
There are overnight trains (with sleeping cars) and overnight ferries too.

Finalizing our trip and just wanted to be sure that we have set aside enough time in each of the places that we would like to visit.
Total trip is 23 days - end of August to September
Starting in Sicily, not including travel days, we will have a full 5 days. Both of us are from here so we will also be visiting family.

Next, Naples, we plan to fly in to Naples and then make our way down to Massa Lubrense, Italy (south of Sorrento I believe) Excluding travel days, we have a full 3 days here.
We want to do day trips to Amalfi and maybe Capri - does this sound realistic? Any recommendations? Ferry over the bus? We love views!
Is it expensive to dine near the AC?

Next we will drive back to Naples, will likely leave early AM and stop for lunch (pizza) in Naples. Then will continue the journey to Rome.
PS we are doing allot of this driving ourselves as my fiance and I love road trips and want to soak in the Italian lifestyle.
We will then drop off the car just outside of Rome - any recommendations of how to get inside the city center from there?
Excluding travel days again, we have a full 2 days in Rome. We are not huge fans of crowds and sight seeing but I definitely want to see some of the major sights.
Do you think 2 days will give us a good taste for Rome? Any recommendations on which location we should stay in? Was thinking near the Trevi Fountain...

Next we will rent another car, outskirts of Rome I guess - maybe can get there by Train, not sure.
We will then drive through Tuscan region to a Agriturismo - any recommendation as to which town has the best views and more relaxed atmosphere?
We may do horseback riding, cooking class and just relaxing when we are here.
Has anyone been to the hot springs? This looks interesting.
We have a full 3 days here - excluding travel days. We plan to go to Venice from here probably by Train...maybe this will effect the recommendation of town?

Last, Venice...We have a full 3 days here excluding travel - is this too much time?
Was thinking to stay in San Marco because of the Canals and convenience by foot.
Do you recommend a hotel or a B&B
Is all of Venice expensive? I have heard from many people that it is and I worry that so many nights will run us over budget.
But then I also thought that there must be restaurants that are not so touristy and expensive.

I appreciate all your feedback!

Three days is so brief for the Amalfi coast. I would consider adding those day to Sicily to cut down on all the moving.
Also, no need to drive from Naples to Rome--it's boring--save the driving for Tuscany. Time to hunker down with a Tuscany guide!
congrats!

Topping for the OP who doesn't know how to find her thread

If you decide to drive to Rome, the best place to drop the car is Fiumicino airport. From there you can take a train or taxi into Rome. You might want to stop at Sermoneta, a very pretty little town with an impressive castle. In fact, I consider Sermoneta to be one of the prettiest towns in Italy.

Another possibile stop would be Montecassino, with a huge monastery, reconstructed after it was bombarded by the Allies during WWII. The seaside towns of Sperlonga, Anzio, and Nettuno are other possibilities, as well as the towns in the Castelli Romani area.

Any one of these stops could be for just a few hours, or a lunch stop. Don't try to do more than one. They're all pretty near Rome.