We leave tomorrow for Paris and are scheduled to return the 20th. I went to the website to check in and see a notice that a strike looms from 3/18-3/20. Should I try to re-book our departure now for the 21st? Wait and see what happens (they say they will text us the day before our flight and cover food and accommodation, though they don't say how much they will reimburse nor how soon we can get out). I think we have the flexibility for a one day delay but are leaving our 6 year old daughter home with the grandparents and can't tolerate a long absence. What would you do?

I should clarify our flight there seems fine, it is the return flight that would be affected.

There are quite a bit of unpredictabilities in this kind of things. Even if the strike ends on the 20th, that does not mean you flight operates as scheduled on the 21st.
I have gone through three of these. Twice, the strike got cancelled at the last minutes. Once my flight was cancelled, but the ticket was issued by Delta, so Delta put me on a much earlier codeshare Korean Air equipment in a roundabout way to get me home. What I did not like was the notifications were not clear and the new flight was not immediately linked to my original online booking. I had to wait and wait to talk to a person at Delta to find out the full booking details. It seems, unlike in the U.S., there are more regulatory incentives to get you to the destination with minimum delay.

And there is no way to know then when we get home...

There are inherent uncertainties in many parts of our life. Traveling involves one uncertainty after another with more impacts than at home as time is usually limited. Even the arrangements you thought you were covered, such as your outbound flight, also can come with an uncertainty like this http://atwonline.com/labor/french-at...-cancellations. By the way, the ATC strikes QUITE often. You can configure your itineraries assuming everything goes as planned. You can also configure in a way to tolerate uncertainties better.

Here is one from their summer strike last year. Not all the flights got cancelled. http://www.france24.com/en/20160729-...sery-thousands.

There are many scenarios. You can get rerouted like this https://www.tripadvisor.com/ShowTopi...de_France.html. You might arrive much later or you might have to leave much earlier. You would have more options if you can tolerate changes in time in both directions.

Short haul or long haul flight? Short haul flights are more affected by these strikes.

good point, the OP is flying from CDG to the US, I believe, so likely it wouldn't be affected anyway by a cabin crew strike

Correct, we are flying from CDG to the US. Now that we are here we are just going to let things play out and see what happens. If they contact us with a cancellation we'll see what happens. It's reassuring to hear long haul flights fare better.

The latest news is that almost no flights have been affected, even short haul.