After making a booking and receiving your reservation number from the hotel via email; can you ring the hotel and make a special request about the room you have booked ie request a room on a higher floor etc?

Yes, you can ring the hotel direct to make a request after booking on Quikbook. The first time I used this service I booked a room in San Francisco and then called the hotel to confirm (they had the reservation, no problems) and then asked about a specific room location. The hotel was most accommodating and didn't not mind that had not booked directly with them.

Thanks Margie.

I've also called the hotels I've booked through Quikbook direct to give them my rewards card member and get credit for my stay.

Yes, whenever you book through the Internet you can call the hotel with special requests, I do it sometimes. Or just to confirm my order went through.