Please suggest the finest hotels with the best locations in these cities.

What are your criteria for both a "finest" hotel and a "best" location. Different people will have different ideas of what constitutes finest and best.

Berlin: Adlon Kempinski, Ritz-Carlton.

Prague: Four Seasons, Iron Gate, Mandarin Oriental.

Thingorjus

We just returned from Berlin on Wednesday.

We stayed at Ritz Carlton, and it was a fantastic hotel experience. The hotel itself is beautiful, and the rooms and bathroom are large and well decorated. The location was convenient and the service was top notch.

We walked over to the Adlon to take a look, and our guide told us she always recommends the Ritz over the Adlon.

I read somewhere (I think) that W has just opened a hotel in Prague. If so, you might want to add that to your list for consideration.

It's not part of a deluxe hotel chain, but we liked the small boutique hotel by the castle called U Zlate Studne.

http://www.goldenwell.cz/