My wife and I are considering staying at the Between Friends B&B in Kitsilano (near 4th Ave and Arbutus) for one night. We'll be spending most of our time in downtown, Stanley Park, and Granville Island. Can anyone provide a recommendation or opinion on this B&B? Our alternate choice is the Salish Drive B&B located on the south side of Pacific Spirit Park. Any recommendation between these two establishments?

I unfortunately have no feedback on the specific places, but if you're only in town for one night, I would chose the 4th/Arbutus location. It will let you see Kitsilano and walk to dinner if you choose. The other location is quite remote from just about everything you want to do in Vancouver.

I very much agree with Cat123.
Having lived within a block or two of 4th & Arbutus for over 25 years I can state unequivocally that it's much more convenient.
Ten minutes walk to Granville Island, 10 minutes to the beach a 10 minute bus ride downtown and as mentioned a plethora of restaurants to choose from.

Thanks for the info. Do you happen to have any info regarding Between Friends B&B? Is it a nice B&B? Thanks in advance for your help.

Living here I've never stayed there but looking @ the site I do know those buildings.
Always seems to be work going on-front yards being torn up/people coming and going and the owners aren't at all friendly or outgoing people from what contact I've had with them.
Something of a noisy busy street in daytime-try for a room @ the back-also both houses have seen better days.
Avoid the restaurant around the corner-Sophie's-an underwhelming even mediocre operation.