My mom & I are getting away at the end of this month & would love to experience a unique culinary tour. Both of us truly enjoy cooking/eating great food & would love to experience the more adventurous culinary side of the San Francisco.
Any recomendations?

Most of the commercial tours are for places like Chinatown and North Beach (or even Fisherman's Wharf) and I could/would not recommend any. If you are interested in a Chinatown tour the Wok Wiz gets favorable reviews, even from locals. In the Kitchen with Lisa does a Berkeley Gourmet Ghetto tour i.e. Chez Panisse territory or a Ferry Building tour that seem less touristy.

I forgot the gourmet chocolate tour with gourmetwalks.com.

You should also check out the Ramekins website - www.ramekins.com - they occaisionally have very good San Francisco foodie tours, typically of Chinatown with a chef. I have yet to go, but have friends that have loved it. Hope that their schedule works with yours.

San Francisco is small enough to get around that you can just make your own culinary tour. What type of cooking do you enjoy? Many Fodorites can probably advice the best places for each category. For example: ZARZUELA for a spanish foodie restaurant on the charming Hyde street cafe/restaurant area. http://www.themenupage.com/zarzuela.html
CRUSTACEAN is for vietnamese seafood right on Polk St & California St. http://www.anfamily.com/Restaurants/...n_sanfrancisco
On the higher scale, you should try Gary Danko, Masa's,& Fleur de Lys which will not disappoint.

I second going to the ferry building to experience a gourmet farmer's market with interesting food joints/stores. http://www.ferrybuildingmarketplace.com/
You may also enjoy a meal at the culinary school in SF for under $30:
http://www.chefs.edu/san-francisco/restaurant.asp

Another ethnic place that just came to mind is the peruvian chicken rotisserie place:
http://limonrotisserie.com/