Hello! I need to drive from The Seattle area to the Boston area as soon as I can. What is the best route?

Why do you need to drive? Fly to Boston and rent a car.
Another option would be to fly to Chicago and take the Lake Shore Limited which leaves Chicago Union Station at 9:30PM every night.
Driving it is I-90 pretty much the whole way.

The best route will be the one with the fewest weather obstacles. Check the weather along the route as you go and be prepared for stops or detours, depending on the situation.

This is the weather website I use: https://www.wunderground.com/

Thank you for the link.

There are non-stop flights on Alaska Air from Seattle to Boston. The flight will be less expensive than the drive (gas, tolls, overnights).

The OP has another thread in which we learn there are two kids and two dogs, so flying is probably out.

Get on I-90 and stay on it all the way. Intellicast - http://www.intellicast.com/Travel/Dr...spx?route=I-90 - shows driving conditions coast to coast. If things turn lousy, hunker down until they improve; detouring to other routes usually doesn't speed things up.

Aside from the high plains, the area probably that will give the most concern is along the Great Lakes between Chicago and Buffalo or so, due to "lake effect" snow that can come fast and deep.

Carry the usual cold weather gear of course - blankets, water, chains, etc.

Yes, that was my post also (2 kids, 2 dogs), I didn't know where my
Post would be answered. So, yes, flying is out. Thank you very much for responding.

I suppose your dogs are over 20 lbs. https://www.amtrak.com/pets?WT.z_va_...isc%20Policies
I did once see a dog over 20 lbs. on the Coast Starlight not in a carrier.

Same answer both threads I-90

Good luck & safe travels!

Thank you everyone...

It's mid winter. Expect black ice & snow.
The most important thing by far: your tires. If possible use winter tires or mud & snow tires. Make sure your tread is good. Have chains with you (carrying them is required across many mountain passes)

Make sure your antifreeze is rated to minus 40 F, and make sure your window washing fluid is also rated for extreme cold (normal windshield fluid will freeze into a glaze on your windshield)

Make sure you know how to dive in snow and ice. Some good sources:
http://exchange.aaa.com/safety/roadw...-driving-tips/
http://www.wsdot.com/winter/
http://www.cartalk.com/content/winter-driving-tips-7

Watch the weather and road reports.
Be ready to hole up in a motel for a few days if needed
It's better to be safe than end up in a crash.