Hi All,
My wife and I will be moving from Greensburg SC to Seattle WA in January leaving in the middle of the month. Which route should we drive? We have a jeep wrangler and a subaru wrx. Google Maps is saying to take I-90W ? Is this the best way to take in January? We only have a small amount of experience in snow/ Icy conditions. Please help. Thank you

How many days do you have for the drive?

I would drive the southernmost route possible until you get to Nevada and then head north.
I'll link a previous (and similar thread) here soon.

Having been stationed in the south, and born/raised in OR/WA and made this drive several times for cross country moves, there is no way I would attempt this drive on I-90 in the winter. Take the southern route and then head north. There was a recent thread on a very similar topic, so you might check that for more information. We would take 10 across the south and then once in CA get onto I-5 north. You still have to content with a few areas around the OR/CA border, so time that for the warmest time of the day to be safe. With limited experience in driving in inclement weather, there is no reason to chance it, IMO.

Looks like your first post; welcome to Fodor's!

There's no way to know what traffic conditions are going to be like; in general the farther north you travel the higher the chances will be that you'll get wintry weather. What compounds things is that all the east-west main routes - with one exception - cross some high-elevation country and/or high mountain passes, which will present a higher likelihood of snow and ice (and high winds when crossing the Great Plains) making travel more difficult.

How much time do you have to make the drive? If you can afford the - roughly - extra day or two that it would take to follow a southern route, then north once you're past the Rockies and Sierras, I would recommend that. Here's one map illustrating this route; note I couldn't find a Greensburg SC so assume maybe it's Greenville? Hope so. https://goo.gl/maps/Rr2Fg71ujsWZmyAu7 . This would take you west on I-20 and I-10 all the way to Arizona, then north through California on Interstate 5. The southerly route would offer a high chance of avoiding snow and ice at higher altitudes; even I-40 in northern Arizona can have blizzards.

Once in California, there's a chance of wintry weather in the California central valley (ice and "tule fog") and a higher chance of snow and icy conditions when crossing the Siskiyou mountains on the California - Oregon border and some of the low mountain passes in southern Oregon (where black ice is a big problem in early morning and evening hours.) If the forecast is for bad weather in that zone, then a detour out to the Pacific coast is not only a solution but a scenic one, with only a minor time penalty. Here's the "almost-guaranteed-snow-free" route - https://goo.gl/maps/nSpXd2B4m3HL6ThG8 .

One benefit of the southern route is that you'll also have longer daylight hours. But the main thing, whichever route you choose, is to hunker down if the forecast is for dangerous weather. A day watching movies in some motel room is a lot better than watching them in a hospital room.

Raleigh, NC to Seattle, WA mid-January HELP

I am with the majority of opinions here-I would take I-10 if the weather looks dicey. If the weather doesn't look too bad you could also take I-20 for part of the route. We did a driving trip in early October a few years back going from NY to Seattle and we hit snow in the Dakotas and MN, so I wouldn't want to try that route in the middle of winter.

Is this trip from Raleigh NC or Greensburg SC? I would take I-40 west as far as Little Rock and then decide whether to take I-30 to tie in to I-20/I-10 or stay on I-40 all the way to Barstow.
There is already snow on Mt. Lemmon outside Tucson.

I don't think there is a "Greensburg" in SC.

Then I would guess he means Greenville SC or Greensboro NC.

I'm guessing the GSP area.
But more important to know, the number of days for the trip. SC it too small for the city location to matter much on this drive.