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Osa or Manuel Antonio

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Hi All,
I have read so much here my head is spinning. This is our first trip and we rarely return because we want to discover new places. We have 10 days and are going to Tortugeuro (Tortuga Lodge) Arenal (Lost Iguana) and I have finally settled on a Manuel Antonio Hotel (Issimo) . Before I make the MA reservation I find I cannot get Bosque del Cabo and the OSA out of my head. So many of you rave about the Osa and BDC but I know I would have to take another small plane and it will add a bit more expense. For those of you who have done both what do you think? We are celebrating our 20th anniversary and I really would like to see lots of wildlife (but no vipers!) OSA of MA? Thank you for your help.

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