Driving in the Czech Republic is very easy; the hardest part will be getting out of Prague. The road signs will not be in English. Place names will be in Czech only. Driving signs are universal so you will be able to understand them and there are not that many of them. Many maps have road signs in the legend. Most of Europe drives on the right side including the Czech Republic.

You must have an International Driving Permit and your original passport (not a copy) with you when you drive.

http://jizdnirady.idnes.cz/vlakyautobusy/spojeni/

Click on "English" and enter the places. As you can see, there is a direct bus from Prague to Jablonec n. Nisou dep. 10 am. Travel time is about one and a half hours.

Are you sure the glass museum is worth the time? I doubt it.

Thanks for the link, Ingo. I can make enough sense of it to understand that there is regular bus service that should meet our needs.

Adrienne, the glass museum is of particular interest for my husband, as he is a button collector and Jablonec was once had a thriving button industry. (Who knew). Since he is quite agreeable with me usually choosing our destinations and activities, I try to accommodate his occasional request. But I do it less happily if we are not properly prepared and waste a lot of time trying to get where we are going. So thank you for the heads up re international driving permit. In looking into that I learned that car rental for someone over 70 can be difficult, which means I would have to drive, and having hubby as a passenger/navigator is not my idea of a holiday. So it will probably be the bus.

The bus is probably the way to do it since you're only going to one place and then back to Prague. I had no idea of the schedules and could only offer driving information.

Enjoy your time at the glass museum. I love offbeat, small museums.