7 Best Sights in Perugia, Umbria and the Marches

The region's most comprehensive art gallery is housed on the fourth floor of the Palazzo dei Priori. The collection includes work by native artists—most notably Pintoricchio (1454–1513) and Perugino (circa 1450–1523). In addition to paintings, the gallery has frescoes, sculptures, and some superb examples of crucifixes from the 13th and 14th centuries.

These elaborate rooms, on the ground floor of the Palazzo dei Priori, served as the meeting hall and chapel of the guild of bankers and money changers. Most of the frescoes were completed by the most important Perugian painter of the Renaissance, Pietro Vannucci, better known as Perugino. He included a remarkably honest self-portrait on one of the pilasters. The iconography includes common religious themes, such as the Nativity and the Transfiguration seen on the end walls. Booking a time for your visit in advance online or by phone is recommended.

A string of elegantly connected palazzi expresses the artistic nature of this city center, the heart of which is concentrated along Corso Vannucci. Stately and broad, this pedestrian-only street runs from Piazza Italia to Piazza IV Novembre. Along the way, the entrances to many of Perugia's side streets might tempt you to wander off and explore. But don't stray too far as evening falls, when Corso Vannucci fills with Perugians out for their evening passeggiata, a pleasant predinner stroll that may include a pause for an aperitif at one of the many bars that line the street.

Severe yet mystical, the Cathedral of San Lorenzo is most famous for being the home of the wedding ring of the Virgin Mary, stolen by the Perugians in 1488 from the nearby town of Chiusi. The ring, kept high up in a red-curtained vault in the chapel immediately to the left of the entrance, is stored under lock and key—15 locks, to be precise—most of the year. It's shown to the public on July 29 (the day it was brought to Perugia) and September 12. The cathedral itself dates from the Middle Ages, and has many additions from the 15th and 16th centuries. The museum displays historical artworks and treasures, plus don't miss walking the underground foundation layers, some of which date to the 7th century BC; book a timeslot online when you buy a ticket.

An excellent collection of Etruscan artifacts from throughout the region sheds light on Perugia as a flourishing city long before it fell under Roman domination in 310 BC. Little else remains of Perugia's mysterious ancestors, although the Arco di Augusto, in Piazza Fortebraccio, the northern entrance to the city, is of Etruscan origin.

A series of elegant, connected buildings serves as Perugia's city hall and houses three museums. The buildings string along Corso Vannucci and wrap around the Piazza IV Novembre, where the original entrance is located. The steps here lead to the Sala dei Notari (Notaries' Hall). Other entrances lead to the Galleria Nazionale dell'Umbria, the Collegio del Cambio, and the Collegio della Mercanzia.

The Sala dei Notari, which dates from the 13th century and was the original meeting place of the town merchants, had become the seat of the notaries by the second half of the 15th century. Wooden beams and an array of interesting frescoes attributed to Maestro di Farneto embellish the room.

A labyrinth of little streets, alleys, and arches, this underground city was originally part of a fortress built at the behest of Pope Paul III between 1540 and 1543 to confirm papal dominion over the city. Parts of it were destroyed after the end of papal rule, but much still remains. Begin your visit by taking the escalators that descend through the subterranean ruins from Piazza Italia down to Via Masi. In summer, this is the coolest place in the city.