Drive from Oakland to Yosemite
#2
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Actually there isn't anything that can't be missed as you go from 580 east to 205 to I5 (briefly) to 120 east. You'll pass east bay towns like Livermore which has a few wineries that might be of interest, the Wind machines of the Altamont pass, the lovely towns of Tracy and Modesto and then into the foothills on your way to Yosemite.
#4
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Petal to the metal all the way - unless you are travelling during the afternoon commute or on a Saturday morning, then it's stop and go (mostly stop) traffic until you get past Tracy. Nothing interesting along the way, just farmland and small towns as other people have mentioned.