Has anyone stayed in a great B&B in the Center of San Fran or in the Knob Hill section? A small boutique hotel might also do. Thansk!

There is no such thing as "knob" hill in SF It's "Nob Hill" no K.

What is your budget?

There are some nice boutique hotels in the Union Square area, which is just down the hill from Nob Hill....but, tell us how much you can spend?

We would like to spend around $200-225 a night. Thanks!

I would definitely check out the Chancellor Hotel, which is a boutique hotel in an excellent location, 1/2 block up Powell Street from Union Square. It has an incredible staff, helpful, friendly, knowledgeable.

The rooms were all refurbished last summer and are small (as fits an older boutique hotel) classy, with walk in closets, a "pillow menu" to choose your firmness, and a rubber ducky for the tub.

There is a small cozy bar area and a small restaurant.

Check out the reviews on Trip Advisor..they are all outstanding. I love to stay here.

Try chancellor.com....that should take you there. Or google Chancellor Hotel San Francisco.