Any suggestions of points of interest between these two places. Am taking a trip with grandchildren, ages 2 - 17 and want to stop along the way for educational and fun times. Low budget. I think Pittsburgh will be our first stop.

It would be really helpful to know what ROUTE you are planning to take. However, have you thought about stopping someplace such as Mammoth Cave in Kentucky?

Akron OH National Inventors Hall of Fame,
Canton, OH Football Hall of Fame
Cleveland OH Rock N Roll Hall of Fame
South Bend, IN College Football Hall of Fame, Studebaker Museum, Notre Dame campus
Indianapolis Childrens Museum, Indy Zoo, NCAA Hall of Fame Indy 500 racetrack
Springfield, IL Lincoln Presidential museum is a must see
ST Louis, Gateway Arch. ST Louis Zoo, Forest Park, Children Museum Has replica of Oval Office, Six Flags (in season)

Dayton Ohio, Boonshoft Museum of Discovery. http://www.boonshoftmuseum.org/
Enough to interest both the youngest and the teenager.

Pittsburgh is way out of the way... take RT 90 through Cleveland and take some of the above stops... Even consider Erie PA for a stop at their indoor WaterPark...