Ahm... auhntiel: If you are an old-time poster, you will have noticed that English isn't hsv's first language.

You would have to be entitled to boast about YOUR second-language vocabulary, if it were as encompassing as hsv's.

To answer the original question, Area 2 of Prague is slightly off centre, and therefore away from the heart of the action. Only you will know how important this is to you. Depending on how long you are staying, you might find that you resent speding all your valuable time getting into the centre to see the things you want to see. On the other hnd, you may enjoy the experience of travelling around to get to places by tram and metro. Only you know!