Sometimes 2 am is way too early. And with a 30-hour dance party starting at 10 pm on Saturday, the EndUp is by far SF's most popular after-hours place, with possibly the best sound system in the city. Said system is cranked. Even the cool kids wear earplugs. It's open nonstop from 10 pm Saturday until 4 am Monday, and generally 10 pm–4 am weekdays It can be a bit of a meat market, but this San Francisco institution doesn't adhere to any particular scene.