The Best Hotel in San Francisco, California

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We've compiled the best of the best in San Francisco - browse our top choices for the top things to see or do during your stay.

THE BEST HOTEL IN SAN FRANCISCO

The St. Regis San Francisco

$$$$ | 125 3rd St., San Francisco, CA, 94103, USA
Fodor's Choice

FODOR’S EXPERT REVIEW

Across from Yerba Buena Gardens and SFMOMA, the luxurious and modern St. Regis is favored by celebrities, business titans and leisure travelers drawn to rooms and suites decorated with leather-paneled headboards; 3D graphic art pieces by Christo Saba; floral touches; and lots of natural light from windows offering city views (suites feature stunning floor-to-ceiling windows). It's no surprise that the design is a main inspiration for the other contemporary/sleek-style St. Regis properties elsewhere around the globe. The spacious bathrooms have deep soaking tubs, plush robes, and steady pressure rainfall showers. The hotel's glamorous restaurant and bar are a favorite gathering spot for the city's power players and C-suite visitors, who seem to appear like clockwork at 6 pm for the nightly champagne sabering celebration.