7 Best Hotels in The Thames Valley, England

To feel like an Edwardian grandee, sweep up the drive to this stately home, one of Britain's grandest hotels, with an opulent interior that includes John Singer Sargent's famous portrait of Nancy Astor, suits of armor, tapestries, and acres of wood paneling. The luxurious, traditional bedrooms, complete with fireplaces, molded ceilings, and antiques, are named after prominent guests, from Charlie Chaplin to Henry James. You can eat contemporary British dishes in the stately Cliveden Dining Room restaurant beneath stunning chandeliers, or more informally at the Astor Grill. Later, take a dip in the beautifully secluded outdoor heated pool. If your pocket doesn't rise to a night here, you can drop in for a luxurious afternoon tea.

An imaginative renovation has transformed this 18th-century mansion, set on 240 acres of parkland, into a playful and contemporary lodging, where tree branches serve as bedposts, a grand copper oak-leaf chaplet is suspended overhead in the restaurant, and carpets echo the colors of leaves. You can listen to underwater music in the spa pool, soak in a copper roll-top tub, watch a polo match, or play a game of croquet. The restaurant, Woven by Adam Smith, has exquisite dining, using as much local produce as possible. The Barn serves more rustic fare, and the Spatisserie specializes in healthy options.

Part Jacobean, part Georgian, this magnificent stately home provides formal luxury in an opulent country setting. The building is decorated with a masterful touch—crystal chandeliers, original oil paintings, and carved ceilings adorn the ornate public areas; the magnificent Jacobean staircase is guarded by unique carved figures. Bedrooms, furnished with well-chosen antiques and comfortable beds, are suitably grand. Some rooms are situated in Hartwell Court, on the approach to the main house, and some have direct access to 90 acres of landscaped parkland. You can dress to impress for dinner, enjoy the terrace of the spa's café, or just drop in for a refined afternoon tea.

Standards are high at this 15th-century stone manor house, the ultimate place for a gourmet getaway, where master-chef Raymond Blanc's epicurean touch shows at every turn, including in one of the country's finest kitchens. The idyllic, 30-acre retreat has a kitchen garden, where vegetables are grown for the restaurant. There's also a valley of wild mushrooms, an herb bed with 70 varieties as well as micro-herbs, an orchard stocked with more than 80 varieties of British apple trees, and a wildflower meadow. Although Let's Cook experiences and garden tours (weekdays only) are popular, and the impeccable dining experience is a big draw for many, the hotel—part of the Belmond collection—stands on its own, whether you're a foodie or not. The accommodations are separated into seven categories and spread out between the main house and garden courtyards. The layout of each room and suite is vastly different; one might be in a dovecote, another might have an Asian-inspired feel with bamboo wood and a scented steam room, and another a private terrace and marble bath. Dogs have their own heated kennels.

You're treated to an exceptional view of Windsor Castle's Changing the Guard ceremony from this former coaching inn, parts of which date from the 16th century. In the older section of the Georgian-style house, guest rooms have gently tilting floors and some suites have standing bathtubs in the room; in the modern part, it's smooth elegance, with tasteful neutral tones enlivened by a judicious sprinkling of red or yellow. The cozy lounges are perfect for afternoon tea.

Although fishing aficionados consider this luxurious, 17th-century, Thames-side inn ideal, the place is stylish enough to attract those with no interest in casting a line. The name comes from Izaak Walton's 1653 masterpiece of angling advice and philosophy, which he wrote in this area. Rooms, traditional in style, are subtly decorated in earth tones with purple touches, and many have views over the Thames. The hotel's Riverside Restaurant serves outstanding Modern British cooking with terrace and waterside views. A sunny conservatory serves afternoon tea.

The Graduate Hotels group took a 19th-century neo-Gothic landmark and gave it a top-down makeover, beautifully amplifying its Oxford heritage and incorporating such stylish guest-rooms touches as William Morris–esque wallpaper, quirky artwork, and nods to the likes of Oscar Wilde and Alice's Adventures in Wonderland. Some of the hip yet elegant, chic yet traditional accommodations have views of Oxford's spires. A tiled, vaulted spa offers pampering treatments designed to ease those travel-related aches.