Do you think that 6 nights in Amsterdam is too long to spend for four people in their 20s and 30s?

Not really. Amsterdam is an incredibly pleasant and youthful town. But for variety's sake, I think splitting the time between Amsterdam and Antwerp for a crowd that age would be a lot of fun, especially since the food and drink is so much better in Belgium. Antwerp is a short train ride away.

Thank you so much for getting back to me. I never even considered Antwerp. Is there a lot to do in terms of nightlife and music in Antwerp?

No, I don't think it is too long. I was there solo 5 nights at the start of one trip. Didn't even scratch the surface.

Not at all. I recently spent 6 days days there and didn't see a lot that I had hoped to.

It's a perfect choice for a group of young adults due to its varied and endless night spots. Great music, great beer, great food and it's compact enough that you easliy walk or tram everywhere.

I would hit a different neighborhood each of your six nights. Definately spend some time in De Piip, the Jordaan, Leidseplein, Rembrantplein, as well as the Old center.

In addition to rock clubs, concerts and the like, spend some time chilling at the brown cafes where you can relax and get to know some locals. The best brown cafes are in De Piip, IMO.

Antwerp has a great bar and music scene. Next to Milan, it is considered the design capital of Europe. And it has better beer! (And truly, much better food.) If you go, do make a visit to Da Vagrant if you like to drink at all.

But do a little research on line about Antwerp. See what you think.

http://tinyurl.com/f8gjg

This may be an even better link:

http://www.dancevibes.be/discotheques.jsp

We were in Amsterdam for 5 nights last June, and loved every minute. We did spend one afternoon taking a tour out of the city. So much to see in Amsterdam, and walking on beautiful canal streets. A very friendly town. Hopefully you'll be there when the weather will be agreeable?
I suppose you've checked into what bands might be in town when you're there, like at the Paradiso? And, if weather permits, there's a nice outdoor venue in the Museumplein.
Here is my trip report:

"LOVED, LOVED, LOVED Amsterdam! You always hear of the Red Light district and the coffee shops and the laissez-faire attitude, but you don’t hear how open and friendly the people are, how lovely the canals and side streets, how wonderfully trendy the restaurants and cafes, how people are out strolling at all hours of the night and you feel safe everywhere. I think I’d expected it to be quaint and charming (which it is), but in a dark wood-paneled cliché way, not in the young and contemporary way it is.

The standard reply we were given in Amsterdam, when we asked for anything, was always “Of course!” How refreshing.

We stayed in a fabulous location, at The Hotel Residence le Coin, which was directly across a small street from the Hotel de l’Europe, down the street from the Hotel Doelan, on Nieuwe Doelenstraat (sp?). A great neighborhood in the heart of old Amsterdam.

The hotel has a lift and A/C, also free use of the hotel’s washing machine and clothes dryer in the basement (which was welcome as we’d been traveling over a week when we arrived there). Each room has a little kitchenette, a nice-sized bath, large rooms with wooden floors and a sitting area. It’s fairly new, so everything sparkles. Very friendly front desk, too.

Two cafes on the same block as the hotel were wonderful: Café Katoen for a university atmosphere, and Café de Jaren, for great table seating on the canal.

Amazing dinners at two restaurants in particular:
“Stout!”, at Haarlemmerstraat 73 (www.restaurantstout.nl). Fabulous ‘foamy asparagus’ soup with shrimp, chateaubriande, fresh fish, dessert course, wine list. Very trendy lighting. Great service. We’d gone to the neighborhood in search of a restaurant called “Lof” which we’d seen written up. We didn’t like its atmosphere, but were lucky that Stout! was just across the street.

Also at “Restaurant Dining Eleven” we had a great dinner. It’s at Reestraat 11. Also trendy and contempory, well-presented and beautifully-served meal.

Another nice dinner at “frenzi”, at Swanenburgwal 232. Very simple and contemporary. We arrived shortly after 10:00p.m., when most restaurants close in Amsterdam, and persuaded the owner to sell us any left-overs they had in the kitchen! They put together a nice Caesar salad with cooked-in-the-shell shrimp and mango. Very nice.

Also a good brunch at a place across the street from frenzi—called “Puccini”. Creative salads and sandwiches. Very nice also.

We took a canal cruise one evening. Toured the Anne Frank Huis and the Van Gogh Museum. Visited the Nieuwe Kerk (sp?) Our teens went to a concert at the Paradiso and loved it.

One afternoon we did the 2:30 “Best of Holland” excursion to Volendam and Marken, with a stop to see wooden clogs made, Gouda cheese created, and to visit windmills. It was by bus, with a boat from Volendam to Marken. A lot of fun. Even our two teens liked it.

Our teens also liked shopping at one street in particular, between our hotel and the museum district. Also a Zara shop there, and many others like it. They thought the selection and prices were better in Amsterdam than what they’d seen in London and Paris even.

A detail about Amsterdam if you go there-- carry enough Euros in cash, because many places won't accept a credit card for a 'small' purchase (i.e. under 25 EU).
The only unpleasantness we encountered in Amsterdam related to cab rides and inconsistent pricing. Especially when our two teens were grossly overcharged cabbing to the hotel from the concert. They were well aware of the route, having walked it already twice, but we'd wanted them to cab home late at night. They knew the cabbie took a very round-about way back in order to over-charge. Also, when we arrived at the taxi sand at Central Station, I was literally swarmed by rather aggressive cabbies and felt uncomfortably jostled by them all."