I will be in Paris with 5 people (husband,wife,3 small children) for 2 nights. Any recommendations of a hotel near Notre Dame or Eiffel Tower that can accomodate 5 people comfortably? Or an apartment that will take daily rentals? Thanks

Citadine Apartments take daily rentals. Check out their website.

Check out the Danube..sounds like your children might be young..they may be able to help you..

http://danubehotel.com/

Only those apartment-hotels will rent a place by the day.

It depends what you mean by comfortable, what standards do you want or budget? Because this hotel is very near Notre Dame and the Maubert metro stop and does have rooms for five:
http://www.hotel-marignan.com/

So, it is comfortable in that they have a real room for five, but it is not a very high-level hotel, rather basic. Someone else on here once said the 3* Hotel des Grandes Ecoles in the Latin Qtr had one room for five people, but I don't know if it still does.

You might try the Hotel Unic St Germain. It's also near Luxembourg Gardens so would be a nice place for small children to run off steam.

http://www.france-hotel-guide.com/h75014unic.htm