My husband and I are looking for a guide, with a car, who can take us to Seville, Granada, Cordoba and Ronda and Antequera. We will stay in one of those cities and use it as a base. In addition to the guide, in which city should we stay? We will be there from October 3 to October 7.
Thank you.

Antequera would be the one to choose as a base as it's more centrally located. For car/driver/guide you may want to talk to Emily Matthews of South Ole Spain Tours. I've used them for simple transfers from city to city.
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Antequera would be the one you should choose as a central base for trips to your other cities, although I personally wouldn't have a base, as Andalucía is very large and very wide. Day trips to Córdoba, Sevilla and Granda from there will still be long days, and the trips there won't be as rewarding as actually spending nights in these very atmospheric and monument/museum rich cities of Al Andalus.

But.... if you decide you must have a base rather than spending nights in your chosen cities, you might want to talk to Emily Matthews of South Olé Tours about arranging a car/driver/guide. I've contacted them in the past about transfers from city to city.
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GerryW,
I just answered your question but my post is in moderation. It should show up later.

Not sure how you are seeing your days. Are you thinking a driver who is also a guide with car for five days to drive you to a new place, show you around and drive you back? IMHO, this is not practical, perhaps not even doable to your chosen places in your time frame.

Except for Cordoba from Seville by train or maybe Ronda or Granada from Antequera, these cities are just a bit too far apart to work as day trips from a central base. It would mean hours on the road with little time to see major sights in any of the places.
You say from Oct 3 - Oct 7. Are you arriving on Oct 2 and departing on oct 8, giving you five full days? Even with that, with travel, you would have, at best, 1/2 to 3/4 day in each city. You might not even be able to book the Alhambra in Granada during that time. With the distance, you would barely have time to visit the Mezquita in Cordoba and just a drive around in Seville. If you are arriving on Oct 3 and departing on Oct 7, the plan is not even possible. You will probably have to choose only three places to visit.

You can book tours at the major sights, like the Alhambra.

Exactly when and where will you be arriving and departing?

My previous post in moderation in a nut shell--it would be exhausting to tour the monument-rich cities of Granada, Sevilla and Córdoba, the treasures of Al Andalus, from Antequera, the only mildly "central point" in this very large, very wide region. A central base just doesn't work for Andalucía.

Yes, tickets for the Alhambra are available for October on https://www.alhambra-patronato.es/en
but... they should be booked far in advance.

Sorry about the triple posts. My first post didn't take into account your short time frame, so a central base really wouldn't be at all practical.

Thank you for writing back so quickly. I already contacted Emily. She is on vacation and will get back to me next week.

Thank you for writing back so quickly. I wrote to Emily and she told me that she is on vacation but will write back next week.
She must be good because multiple people who replied to me have recommended her services.
We have a limited amount of time in the region and are trying to maximize what we can see while we are there.
Thanks again.

Thank you for writing back so quickly. We arrive on October 3 and leave on October 7. At this time I do not know if we are taking the train or flying. Regardless, the reason we want a guide who also drives is that we want to maximize our time in the area. We know we are limited but we want to do the best we can within our limited time. Any suggestions would be appreciated.
Thanks again.

You can post mutliple times to us. We appreciate any and all suggestions.
We arrive on October 3 and leave on October 7 and realize we do not have a great deal of time to see everything. The reason we want a guide who also drives is because we want to maximize the time that we have. Any suggestions would be appreciated.
Thank you.

Thank you for writing back so quickly. We arrive on October 3 and leave on October 7. At this time I don't know if we will fly or take the train. The reason we want a guide who also has a car is that we want to maximize our time while in the area. Any suggestions would be appreciated.
Thanks again.

Having spent a week near Antequera I will just say what the others have said, which seems to not be getting through, to "maximize" your short time in a large area, visit fewer places & spend far less time on the road. I think as now conceived this trip would be a waste of time with considerable expense being driven through the countryside for hours, though I do like that countryside.

I think you've grossly underestimated the distances & overestimated the time you actually have to accomplish your plan. Rethink it so it becomes a satisfying experience. As planned now you have just 3 full days, the 4th, 5th & 6th.

With the new clarification of your actual dates -- Sassafrass is spot on with the post "If you are arriving on Oct 3 and departing on Oct 7, the plan is not even possible. You will probably have to choose only three places to visit"

we were posting at the same time . . .

With such a short time frame, you need to base in cities you can fly into or take a train to for arrival and departure, not cities that would require more hours of travel to reach initially. Now that we know you really have only three full days, what are your two must see places? Plan to arrive in one and depart from the other. Then see if a third stop can be made in between.
Some Options: there are others, like Ronda instead of Granada or Cordoba, depends on your priority.
1. Arrive Seville (train or plane) and visit Cordoba by train as a day trip. Depart from Seville
2. Arrive in Cordoba by train, train to Seville, depart from Seville.
3. Arrive in Seville, train, bus or private driver to Granada. Depart from Granada.
4. Arrive in Granada by plane. Have Private driver pick you up after visiting Granada and stop in Cordoba for 1/2 day in route to Seville.

Having a car and driver will not help you to see more in this situation. I am sorry about that, but it is true.

" . . .we want to maximize the time that we have."

Driveing hours each day only maximizes the time you have . . . IN the car. You really do need to cut back your wish list.

Fully agree.

It seems you have picked the places which interest you, but not really sorted out geographical logistics or how much time is needed to actually see them. Sometimes, it is tough to realize a plan is not going to work. Perhaps people could offer interesting alternatives if you share different/more information about your trip. Is this just one leg of a larger trip? Will you already be someplace else in Spain before the start of this trip or in another country in Europe? If so, where? What is your destination after this bit?