Heading to Barcelona for a couple of nights before a cruise in October and looking for hotels near the cruise ship port. Also, concerned about transportation between the downtown and the port area. Is it best to take the Port Bus or is there other transportation I should consider? And, want to catch a few sights like Sagrada Familia, Guell, and Montjuic Cable Car/Port Cable car. Just hoping there is enough time

Barcelona cruise port is not far from city center.
You may just stay in any hotel you like in Eixample, and take a taxi to the cruise port on the embarkation day. There is no need to stay close to the port.

Thanks.