Don Antenor Patiño, the Bolivian "Tin King," inaugurated this Mexico City classic in 1969 and named it after his granddaughter, socialite Isabel Goldsmith. The stunning marble lobby has gleaming brass fixtures. All guest and public rooms are impeccably maintained; the former have extra comfy Posturepedic mattresses and goose-down pillows. Penthouse suites in the 22-story tower are extra-spacious and have butler service. Pros: The location—across from the Angel Monument and the Zona Rosa, with Sanborns next door and the U.S. Embassy a half block away—is prime. Cons: Some areas need some TLC, unexpected charges.
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