In the Alfama district, narrow, twisting streets and soaring flights of steps wind up to an imposing castle on one of the city's highest hills. This is a grand place to get your bearings and take in supreme views. Because its foundation is dense bedrock, the district—a jumble of whitewashed houses with flower-laden balconies and red-tile roofs—has mostly survived the wear and tear of the ages, including the great 1755 earthquake.

The timeless alleys and squares have a notoriously confusing layout, but the Alfama is relatively compact, and you'll keep circling back to the same buildings and streets. Although now a somewhat run-down neighborhood, it has a down-to-earth charm—particularly during the June festivals of the Santos Populares—and smart bars and restaurants are slowly moving in.

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