Loreto is famous for one of the best-loved shrines in the world, that of the Santuario della Santa Casa (House of the Virgin Mary), within the Basilica della Santa Casa. Legend has it that angels moved the house from Nazareth, where the Virgin Mary was living at the time of the Annunciation, to this hilltop in 1295. The reason for this sudden and divinely inspired move was that Nazareth had fallen into the hands of Muslim invaders, whom the angelic hosts viewed
as unsuitable keepers of this important shrine. Excavations made at the behest of the Catholic Church have shown that the house did once stand elsewhere and was brought to the hilltop—by either crusaders or a family named Angeli—around the time the angels (angeli) are said to have done the job.
The house itself consists of three rough stone walls contained within an elaborate marble tabernacle. Built around this centerpiece is the giant basilica of the Holy House, which dominates the town. Millions of visitors come to the site every year (particularly at Easter and on the December 10 Feast of the Holy House), and the little town of Loreto can become uncomfortably crowded with pilgrims. Many great Italian architects, including Bramante, Antonio da Sangallo the Younger (1483–1546), Giuliano da Sangallo (circa 1445–1516), and Sansovino (1467–1529), contributed to the design of the basilica. It was begun in the Gothic style in 1468 and continued in Renaissance style through the late Renaissance. The bell tower is by Luigi Vanvitelli (1700–73). Inside the church are a great many mediocre 19th- and 20th-century paintings but also some fine works by Renaissance masters such as Luca Signorelli and Melozzo da Forlì (1438–94).
If you're a nervous air traveler, you can take comfort in the fact that the Holy Virgin of Loreto is the patron saint of air travelers and that Pope John Paul II composed a prayer for a safe flight—available here in a half-dozen languages.
Piazza della Madonna, Loreto, 60025, Italy