The 13th-century Collegiata church has three majestic portals, one possibly the work of Giovanni Pisano (circa 1245/48–1318). Behind the high altar are some fine examples of inlaid woodwork by Antonio Barilli (1482–1502). In the floor of the left aisle, look for the tomb slab of Henry of Nassau, a pilgrim knight who died here in 1451.
- Address: Piazza Chigi, San Quirico d'Orcia, 53027
- Phone: /
- Hours: Daily 8:30–12:30 and 3–7
- Location: San Quirico d'Orcia