Chablé Yucatán
Set on 740 acres, this meticulously restored hacienda is the state's most expensive resort, but it's a splurge-worthy choice—not only does it have spacious, luxuriously appointed, freestanding villas but it also makes an elegant base for exploring Mérida, a 40-minute drive north, as well as area Maya sites, including Oxkintok, Yaxcopoil, and Uxmal. The decor is contemporary with Mexican accents, the spa is world class, and there are delightful details at every turn—from honey made on-site to the world's largest collection of tequilas.