5 Best Sights in Sant'Ambrogio, Milan

Leonardo da Vinci's The Last Supper, housed in this church and former Dominican monastery, has had an almost unbelievable history of bad luck and neglect. Its near destruction in an American bombing raid in August 1943 was only the latest chapter in a series of misadventures, including—if one 19th-century source is to be believed—being whitewashed over by monks. After years of restorers patiently shifting from one square centimeter to another, Leonardo's masterpiece is free of centuries of retouching, grime, and dust. Astonishing clarity and luminosity have been regained, helped by lighting, and a timed entry system where small groups are ushered into climate-controlled rooms with automatic glass doors, to prevent humidity.

Despite Leonardo's carefully preserved preparatory sketches, in which the apostles are clearly labeled by name, there still remains some small debate about a few identities in the final arrangement. There can be no mistaking Judas, however—small and dark, isolated from the terrible confusion that has taken the hearts of the others. Reservations are required to view the work. Viewings are in 15-minute timed-entry slots, and visitors must arrive 30 minutes before. Reservations can be made online. Reserve at least three weeks ahead if you want a Saturday slot, two weeks for a weekday slot. Some city bus tours include a visit in their regular circuit, which may be a good option.

Milan's bishop, St. Ambrose (one of the original Doctors of the Catholic Church), consecrated this church in AD 387. St. Ambroeus, as he is known in Milanese dialect, is the city's patron saint, and his remains—dressed in elegant religious robes, a miter, and gloves—can be viewed inside a glass case in the crypt below the altar. Until the construction of the more imposing Duomo, this was Milan's most important church. Much restored and reworked over the centuries (the gold-and-gem-encrusted altar dates from the 9th century), Sant'Ambrogio still preserves its Romanesque characteristics, including 5th-century mosaics. The church is often closed for weddings on Saturday.

Next to the Museo Civico Archeologico, you’ll find this little gem of a church, constructed starting in 1503 and decorated almost completely with magnificent 16th-century frescoes. The modest exterior belies the treasures inside, including a concealed back room once used by nuns that includes a fascinating fresco of Noah loading the ark with animals, including two unicorns.

Appropriately situated in the heart of Roman Milan, this museum housed in a former monastery displays everyday utensils, jewelry, silver plate, and several fine examples of mosaic pavement from Mediolanum, the ancient Roman name for Milan. The museum opens into a garden that is flanked by the square tower of the Roman circus and the polygonal Ansperto tower, adorned with frescoes dating to the end of the 13th and 14th centuries that portray St. Francis and other saints receiving the stigmata.

This converted cloister is best known for the collection of models based on Leonardo da Vinci's sketches. One of the most visited rooms features interactive, moving models of the famous vita aerea (aerial screw) and ala battente (beating wing), thought to be forerunners of the modern helicopter and airplane, respectively. The museum also houses a varied collection of industrial artifacts, including trains, and several reconstructed workshops, including a watchmaker's, a lute maker's, and an antique pharmacy.