Sant'Ambrogio Travel Guide
  • Photo: Luca Grandinetti / Shutterstock

Sant'Ambrogio

If the part of the city to the north of the Duomo is dominated by its shops, Sant’Ambrogio and other parts to the south are known for their works of art. The most famous is Il Cenacolo—known in English as The Last Supper. If you have time for nothing else, make sure you see this masterpiece. You will need reservations to see this fresco, which is housed in the refectory of Santa Maria delle Grazie. Make these at least three weeks before you depart for Italy, so you can plan the rest of your time in Milan.

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