Cartesiano Boutique & Wellness Hotel
Occupying a magnificently transformed pair of 17th-century buildings, one of which formerly held a ceramic-tile factory, this plush urban oasis with a rooftop pool and a soothing spa is part of Puebla's new wave of chic—and surprisingly affordable—boutique hotels. The hotel is on a beautiful street in Centro Histórico, just a block from the craft shops of colorful Sapos Alley. Artfully outfitted rooms contain plenty of modern perks, including minibars stocked with complementary beverages. There are two fantastic restaurants in the hotel, including the celebrated Salón Mezcalli. This is a sister property to the exclusive Chablé Resort & Spa, near Mérida in the Yucatan.