3 Best Hotels in Ladakika, Thessaloniki and Central Macedonia

An elegant retreat with a touch of history, this exquisite boutique hotel occupies one of the few buildings that survived the great fire of 1917 untouched—during Ottoman rule the structure served as the city's post office—and, today, a mixture of handmade furniture, hand-picked antiques, and works of art makes this place special. Their spacious rooms are named after important Macedonian personalities such as Alexander the Great, Perseus, and Aristotle. The Bristol straddles the Ladadika and Kentro neighborhoods, near the waterfront, right in the thick of things, so it's ideally located for exploring the city.  The trendy Loupino, sharing the ground floor with the Bristol, is one of the more decent restaurants in the area.

Also known as the "blue mansion," this lovingly restored 20th-century listed building has become the chic location to stay in this area. The blue theme continues inside, as a deep Wedgewood highlights the marble staircase leading up to the rooms. The bright art deco lobby has a 24-hour reception where you might be graciously upgraded if a better room is available for the length of your stay. The period contextual rooms all have their own flavor, with soft blues, salmon, and reds.

From the abundance of amenities at this traditionally decorated, six-story hotel near the port and Ladadika, it's easy to see that the Mediterranean Palace caters to business travelers (there are ample meeting and conference areas) who will appreciate the consistently good service and many amenities like the fit center and highly regarded spa. The chandeliers, black marble-top tables, and richly upholstered furniture are meant to evoke aristocratic 1930s Thessaloniki. Everything is bright and shining, and the polish extends to exemplary service. The hotel's fine dining Cookoo restaurant serves up international flavors.