Let me put in a plug for Austin. Winter here is usually quite mild, with temps above 66 not common but not uncommon. Spring/Summer/Fall definitely meet your minimum 66 degree requirement. It does get hot in Austin, but rarely hot and humid (usually the hottest weather is also the driest). Hill Country is pretty, filled with live oaks and cedar trees and plenty of lakes.

I think you, being from Canada, probably would want to experience something quite different than Canada. I think Austin would offer that. I know quite a few people from Canada, and they moved down to Austin and love it.

Another plus for Austin is that it is a great place for people right out of college. There's great nightlife, great singles clubs, groups doing everything from sports, to hikes, to wine tastings, to museum viewings, to cultural festivals, to yoga, etc... Every weekend you'll have things planned with your friends doing fun things that you couldn't do most places... Although there are many native Texans, you'll also find people from all over the country and the world, lending itself to a cosmopolitan, yet rooted feel. The people are also among the most accepting I've found in the US.

I think the Southeast would be too humid for you, based on your requirements, and may be too foreign to what you are used to, and only San Diego/LA would meet your requirements in the Southwest, so you may want to look at that as well. AZ/NM would also partially meet your requirements because it doesn't get humid there, although it gets hot there, but maybe too hot for you. That's why I think Austin would be a good compromise.

Portland, OR is another alternative. We rarely get temperatures over 100 degrees, and summers are pretty comfortable. We usually get at least one day of snow a winter but there are transit options available if you prefer not to drive in the snow.

I think Salem would be a great town for a young single person to live. Lots of great restaurants, music and outdoor recreational opportunities.

Cities in Pacific NW don't meet minimum 66 degree temp requirement most of the year. Just saying...

Being a pharmacist puts you in a very specific position.
First you have to pass the baords in the state you want to live in. (No -many states do not have recirprocal licensure. I have several friends who are paharmacists and looking to semi-retire - to many of he areas you're looking at. To avoid having pharms from other states do this those states require a license from each state in order to work ther - that is FL and Ax and CA do not recognisze NY licenses - to protect locals who are working full time.)

Second - a working visa is different from a student visa - so you definitely need to get th einfo and get that all in order. (My company rquies you to fill in place of birth, nationality and prove you have the right to work in the US before they wil even interview you except for interns that we take from our ex-US offices for 3 months at a time.)

And granted there is a shortage of pharmacists in some places - but that is usually either retail (can you bea having to churn 300 Rx per day?) or city/municipal hospitals that don;t pay very well. The better jobs are not that easy to get.

I'm from Minneapolis which has all you'd require except the weather because we've got long, cold winters here. But, I know some people in pharmacy here, and the jobs have pretty much dried up here because it is a mecca for people from all over the midwest. So, I think you'd need to make sure there really are jobs, and jobs that could support your visa needs, where you think to locate. And, let me tell you, dealing with the bureaucracy of the US to come in as a non-citizen and work is an immense amount of paperwork hassle.