St. Louis has three major neighborhoods. The Hill is known for its good restaurants—mostly Italian—and simple old-world charm. The neighborhood is bounded by Hampton Avenue on the west and Kingshighway on the east, south of Interstate 44. You'll know when you've reached the Hill because the fireplugs are painted green, white, and red. Baseball legends Yogi Berra and Joe Garagiola grew up playing stickball on these streets, but today you're more likely to see a game of boccie—Italian lawn bowling—played at local pubs.
Soulard is a French neighborhood, bounded by the Mississippi River to the east and Interstate 55 to the north and west. There are many reasons to come to Soulard, including the Bastille Day celebrations and Mardi Gras—but the main draw is Soulard Market, where St. Louisans have come since 1779 for the fresh produce, baked goods, and exotic spices, Wednesday through Saturday.
The Central West End, between Forest Park and Page Avenue, is a chic neighborhood filled with trendy boutiques, cozy sidewalk cafés, and galleries. Many of the early 20th-century homes are on display during the annual Greek Festival, held during Labor Day weekend. St. Louisans often stop here after work for a drink or dinner, but the Cathedral of Saint Louis and its collection of mosaic art are worth a visit as well.
Downtown sights can be explored on foot. To visit other parts of town, you'll need a car.