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Panama City's after-dark offerings range from a quiet drink on historic Plaza Bolívar to dancing until dawn at one of the clubs on Calle Uruguay, with plenty of options in between. Although there are bars everywhere, nightlife is concentrated in Casco Viejo, El Cangrejo, and Calle Uruguay, though there are also a few options in the Area Bancária and Punta Paitilla.
Casco Viejo is the city’s nightlife epicenter, with a variety of bars and clubs that rock into the wee hours on weekends. The Calzada de Amador is the place to head for a quiet drink with lovely ocean views. The streets around Calle Uruguay are packed on weekends, when a predominantly young crowd fills its bars and dance clubs. There are also a few night spots in El Cangrejo and Punta Paitilla, where a couple of hotel bars have amazing views.
The nicest casinos are in, or next to, the city's big hotels, namely the Panama Marriott, Veneto, Trump Ocean Club, and El Panamá, and often have excellent bands performing Latin music in their bars.
The city's dance clubs play a broad mix of music that includes pop, salsa, reggaetón, and house music. Cover charges run between $5 and $10, and sometimes include a drink.
There are also strip clubs, locally called "nightclubs," scattered between the Area Bancária and El Cangrejo, which have traditionally catered to business travelers, but are becoming a bit of a tourist attraction in their own right. Prostitution is legal in Panama, but streetwalking is not, so representatives of the world's oldest profession gather at a few of its bars and casinos.
The rooftop bar of this hip hotel has a great view of the city's skyline beyond the ancient roofs of Casco Viejo. Weekends vibrate with the boom-boom of deafening house music, though the quality of the DJs varies. You can get a relatively quiet drink here Sunday through Wednesday.
This pool bar and grill on the 13th floor of the Trump Hotel is a popular weekend spot, thanks to its impressive view of the sea and the skycrapers of Costa del Este. An elevator at the back of the building offers access to the bar for nonguests.
The pool bar on the roof of the Manrey Hotel is a popular weekend spot. DJs pump the crowd up and the danger of somebody falling into the pool increases with every martini served. The glowing-blue lap pool is surrounded by canopy couches, arm chairs, and tables, beyond which twinkle the city lights, making it a splendid spot for a drink any night.
El Pavo Real Panamá is an attractive, British-inspired pub on a quiet stretch of Vía Argentina. It has a long bar, indoor and outdoor seating, two pool tables, and serves bar food including fish-and-chips. They often have live music, mostly rock, on weekends, but you can always get a quiet drink on the front terrace.
Istmo Brew Pub, next to Sevilla Suites hotel, serves several overpriced home brews, as well as the city's best selection of imported beers. It's a popular spot, with seating out front, inside, and on a back patio. There are pool tables and music. Sample the beers before ordering a house brew.
Kayuco is a popular open-air bar and restaurant on the southwest corner of the marina on Isla Flamenco, with a view of the boats and the city's skyline in the distance. It's one of the few spots on the causeway for a drink by the water, and they serve fried seafood and other snacks into the wee hours.
This French restaurant on Plaza Francia has tables on the plaza and a bar inside one of the Bóvedas (arched, brick chambers dating from the colonial era) that often features live jazz on Friday night and salsa music on Saturday. Call to confirm the evening's entertainment.
This large lounge, located in the Radisson Decapolis hotel, was once one of the city's hottest lounges, but it's now a nice spot for a quiet drink.
Cuban music, a massive, hardwood bar, and walls covered with photos and paintings of Cuba make it easy to imagine you're in Havana's old quarter as you sip a mojito.
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