Driving is preferable to relying on public transportation here, as some sights are on secondary roads where bus service is scarce. Highway conditions are good, and most destinations are signposted in both Hebrew and English. The steep road between Arad and Ein Bokek has one hairpin turn after another. Unless otherwise posted, stick to the intercity speed of 90 kph (56 mph). Budget extra time for leaving Jerusalem during rush hours. Gas stations are plentiful; some are open 24 hours, but play it safe and keep the tank at least half full.
If you plan to drive to areas controlled by the Palestinian Authority, several East Jerusalem car-rental companies have insurance for the West Bank. Always check whether there’s political unrest that could make roads unsafe. Throw a keffiyeh, the traditional checkered headscarf, onto your dashboard for extra security.