Yes, rent a car once you leave the AC. Your possibilities are wide open then, especially since you'll be traveling through Tuscany. Familiarize yourselves with the rules of the road, how to read signage etc and you'll be fine. I've driven all over and it's been very enjoyable. One of you should be the navigator - it helps a lot. :)

Sorry to disagree with the above, but do not rent a car until you leave Rome or Florence, depending on your final itinerary. Traffic around Naples can be a mess. You don’t have time for wandering between the AC and Rome. You for sure do not want a car in Rome!!

We're probably going to drive only in Tuscany during the Lupaia portion. Just trying to determine if we should drive to Lupaia from Chiusi-Chianciano-Terme (we'd take the train from Rome to here) or from Florence given it's between the two locations. After being in Rome last time i'd probably not feel comfortable driving.

I apologize for my lack of clarity. I would not recommend having a car while in Rome, I was referring to picking up in or leaving out of. Same for Florence. There's no need for one while staying in either. I was more referring to driving through and around Tuscany.

Small point on grammar: There is no such thing as I's. Simply say 'planning for my honeymoon' and we will assume you are not leaving your freshly minted spouse at home. Even though that would save on expenses.

Siena is one of my favorite places in Europe. I like it better than Florence, and it would be completely new for the both of you.

Shelemm, we've been cleaning out my late mother's house and in her hobby room we found various items from her many travels.
She had 5 or 6 old maps of Sienna plus a bevy of business cards plus pamphlets. She was a professional artist. Apparently once in Sienna, she traded one of her sketches for a free lunch.

OP BL, there are many things to do along the Amalfi coast, especially if one eschews the most touristy 'Insta' centers of commerciality.
I am done. the end

LOL! Thank you for the correction! Been a while since my last english class :lol: Last time I went to Florence, I saw the cathedral in Siena and went to San Gimignano, it was so beautiful!