If you've got the money for it, this 1912 Tuscan villa on 600 lush acres 5 mi east of Charlottesville is a luxurious, cosmopolitan retreat. Since it is now owned by the Orient-Express, you can expect the ultimate in top-drawer amenities and service. The 48 guest rooms and suites contain modern amenities like high-speed Internet and flat screen TVs, which exist in harmony with English and American antiques and claw-foot tubs. Some rooms have whirlpool baths and balconies.
The 18-hole golf course, designed by Arnold Palmer, spreads across the rear of the estate. There's no check-in desk here; you are welcomed inside as if you are entering someone's home. The facilities of the private Keswick Club are open to those staying overnight.