A grouping of barrier islands and salt marshes, this refuge of 66,287 acres was established in 1932 as a migratory bird haven. The Sewee Visitor & Environmental Education Center has information and exhibits on the refuge and its trails, as well as an outdoor enclosure housing four red wolves. Currently, the refuge is aiding the recovery of the threatened loggerhead sea turtles, and a turtle-hatchling video details the work. From the mainland refuge, take a ferry
ride ($40) with Coastal Expeditions from Garris Landing to Bulls Island. There are also four scheduled tours each year to Lighthouse Island—call the Sewee Center for dates and cost.