Occupying its own 10-story building, this branch of the storied UK auction house is the site of more than a hundred high profile auctions a year. You don't have to bid to view items on auction; most items are displayed for the general public in the days leading up to the event. A sizeable portion of these are extremely high profile: Edvard Munch's The Scream, Paul Cezanne's Les Pommes, a copy of the Magna Carta, Fabergé eggs, and rare Tiffany lamps have all been sold through this Sotheby's. Call ahead for hours and check the website for current exhibitions. There have been rumors swirling around the possible sale of this building—and relocation of Sotheby's headquarters to the Hudson Yards downtown—for years, check this out while you can.Tip: The top floor cafe has decent coffee, a terrace (weather permitting), and city views.