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Barges still ply the slow-moving Wicomico River between the Bay and Salisbury, the Eastern Shore's second-largest port after Baltimore. This urban center is a hub of commercial activity in the region and the home of Salisbury University, but its leisure options pale compared to the excitement of nearby Ocean City. The tree-shaded waterfront draws bikers and shoppers. Antiques shops and
galleries, along with some exemplary Victorian architecture, fill its downtown six blocks.
Berlin—named not for the German city, but evolving from Burleigh Inn, a Colonial-era way station—is a short drive from Ocean City, yet it could...