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Iowa’s range of hotels is vast, from adorable bed-and-breakfasts tucked into mansions or Victorian homes in the Quad Cities to reliable chain hotels in pockets around the state, along with chic stays in college towns and Des Moines. It’s what you’d expect from a region that caters to tourists and business travelers alike. Be wary of football weekends in towns like Iowa City and Ames, when alumni and football fans snag rooms months in advance.