A 14,000-acre private ranch in the highlands of East Molokai, Puu O Hoku was developed in the 1930s by wealthy industrialist Paul Fagan. Route 450 ambles right through this rural treasure with its pastures and grazing horses and cattle. As you drive slowly along, enjoy the splendid views of Maui and Lanai. The small island off the coast is Mokuhooniki, a favorite spot among visiting humpback whales, and a nesting seabird sanctuary. The ranch has limited accommodations, too.