To get a feel for what this part of Florida was like before civil engineers began draining the swamps, drive 17 miles east of North Naples to these 13,000 acres of pine flatwood and cypress, grass-and-sedge "wet prairie," saw-grass marshland, and lakes and sloughs filled with water lettuce. Managed by the National Audubon Society, the sanctuary protects North America's largest remaining stand of ancient bald cypress, 600-year-old trees as tall as 130 feet, as well as endangered birds, such as wood storks, which often nest here. This is a favorite destination for serious birders and is the gateway to the Great Florida Birding and Wildlife Trail. If you spend a couple of hours to take the 2¼-mile self-guided tour along the boardwalk, you'll spot ferns, orchids, and air plants, as well as wading birds and possibly alligators and river otters. A nature center educates you about this precious, unusual habitat with a dramatic re-creation of the preserve and its creatures in the Swamp Theater.