Palm Beach, with Gatsby-era architecture, stone-and-stucco estates, extravagant landscaping, and highbrow shops, can reign as the focal point for your sojourn any time of year. From Palm Beach, head off in any of three directions: south via the Gold Coast toward Boca Raton along an especially scenic route known as A1A, back to the mainland and north to the barrier-island treasures of the Treasure Coast, or west for more rustic inland activities such as bass fishing and biking on the dikes around Lake Okeechobee.