San Francisco is generally a safe place for travelers who observe all normal precautions. First, avoid looking like a tourist. Dress inconspicuously, remove badges when leaving convention areas, and know the routes to your destination before you set out. Use common sense and, unless you know exactly where you're going, steer clear of certain neighborhoods late at night: the Tenderloin, Civic Center plaza, parts of the Mission (around 14th Street, for example, or south of 24th to Cesar Chavez Street), and the Lower Haight should be avoided, especially if you're walking alone.
Like many larger cities, San Francisco has many homeless people. Although most are no threat, some are more aggressive and can persist in their pleas for cash until it feels like harassment. If you feel uncomfortable, don't reach for your wallet.
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