Primarily for business travelers, this hotel between Seaport Village and the convention center is San Diego's largest, and its 33- and 40-story towers make it the West Coast's tallest waterfront hotel. Be sure to catch at least one sunset from the 40th-floor Top of the Hyatt bar. All rooms have water views, iPod docking stations, modern furnishings, and windows that open to the coastal breeze. The outdoor pool has cabanas and fire pits. The trolley station is one block away, and the Gaslamp's clubs and restaurants are within walking distance.