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The desert resort communities occupy a 20-mile stretch between Interstate 10, to the east, and Palm Canyon Drive (Highway 111), to the west. The region is about a two-hour drive east of the Los Angeles area and a three-hour drive northeast of San Diego. It can take twice as long to make the trip from Los Angeles to the desert on winter and spring weekends because of heavy traffic. From Los Angeles take the San Bernardino Freeway (Interstate 10) east to Highway 111. From San Diego, Interstate 15 heading north connects with the Pomona Freeway (Highway 60), leading to the San Bernardino Freeway east.

To reach Borrego Springs from Los Angeles, take Interstate 10 east past the desert resorts area to Highway 86 south to the Borrego Salton Seaway (Highway S22) west. You can reach the Borrego area from San Diego via Interstate 8 to Highway 79 through Cuyamaca State Park. This will take you to Highway 78 in Julian, which you follow east to Yaqui Pass Road (S3) into Borrego Springs.

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