Once a vast, open space dotted with horse ranches, Northwest Tucson is now a rapidly growing residential area encompassing the townships of Oro Valley and Marana. Families and retirees are moving here in droves, and the traffic congestion proves the point, but you'll also find the oases of Tohono Chul Park and Catalina State Park, which calm the senses.
If you're interested in the flora and fauna of the Sonoran Desert—as well as some of its appearances in the cinema—heed the same advice given the pioneers: go west. A good idea is to start the morning at Saguaro National Park and then head over to the Arizona-Sonora Desert Museum, where you can lunch at the Ironwood Terrace or the more upscale Ocotillo Café. How long you spend at Saguaro National Park depends on whether you choose a short walk to see petroglyphs at Signal Hill on the Loop Drive (an hour should suffice), or hike a longer mountain trail, but leave yourself at least two hours for your visit at the Desert Museum. The hottest part of an afternoon can be spent ducking in and out of attractions at Old Tucson Studios or enjoying the indoor sanctuary of San Xavier mission, although the mission is also a good stop if you're heading out of town to Tubac, Tumacácori, and Nogales.