Once the only museum dedicated to the Panama Canal, the Museo del Canal Interoceánico has been put to shame by the visitors' center at Miraflores Locks. The museum is packed with artifacts, paintings, photographs, and videos about the Panama Canal, but, unfortunately, the information is only in Spanish, so you may want to spend $5 for a recorded tour in English. Though the building was constructed in 1875 to be the Gran Hotel, it soon became the offices of the Compagnie Universelle du Canal Interoceanique, the French company that made the first attempt to dig a canal in Panama. After that effort went bust, the building became government property, and before being converted to a museum in the 1990s it was the central post office.
Plaza Catedral, Panama City, Panama